a case of progressive rhino-orbital mucormycosis involving the brain via direct extension, retrograde perineural spreading and middle cerebral artery vasculopathy
نویسندگان
چکیده
introduction rhino-orbito-cerebral mucormycosis is a progressive angioinvasive fungal disorder which almost always complicates immunocompromised patients. case presentation we described a case of fulminant rhino-orbito-cerebral mucormycosis in a 65-year-old woman, who presented with progressive neurological deficits due to involvement of orbital apex and the central nervous system by local invasion of the left inferior frontal lobe, retrograde perineural spreading to the brain stem and middle cerebral arteries thrombosis. discussion early diagnosis is mandatory in managing of this life-threatening disorder. urgent surgical debridement associated with antifungal agents (amphotericin with posaconazole) is the mainstay of treatment.
منابع مشابه
Rhino-orbital-cerebral Mucormycosis
Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand. Received for publication: February 7, 2011. Reprint request: Prawat Chantharit, B.Sc.(Pharm), M.D., Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand. INTRODUCT...
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عنوان ژورنال:
archives of clinical infectious diseasesجلد ۹، شماره ۳، صفحات ۰-۰
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